相关实验视频

Updated: Jul 26, 2026

Operant Sensation Seeking in the Mouse
08:39

Operant Sensation Seeking in the Mouse

Published on: November 10, 2010

13.4K

在基因多样化的小鼠群体中,静脉可卡因自我管理的多个阶段的行为变化

Price E Dickson1,2,3, Udita Datta1,2, Troy D Wilcox1,2

  • 1Mammalian Genetics, The Jackson Laboratory, Bar Harbor, ME, USA.

Psychopharmacology
|September 15, 2025
PubMed
概括

高多样性的小鼠模型揭示了对可卡因成进展的遗传影响. 在不同小鼠种群中使用可卡因自我管理的研究发现了物质使用行为中的显著菌株和性别差异.

关键词:
收购 收购 收购吸毒成 吸毒成 是一种成.协作跨界合作方式灭绝的灭绝 灭绝的灭绝遗传学 是一个遗传学.恢复估值是指恢复估值.自主管理的自治.药物使用障碍物使用障碍物

更多相关视频

Methods for Intravenous Self Administration in a Mouse Model12:09

Methods for Intravenous Self Administration in a Mouse Model

Published on: December 8, 2012

55.0K
Assessment of Cocaine-induced Behavioral Sensitization and Conditioned Place Preference in Mice10:28

Assessment of Cocaine-induced Behavioral Sensitization and Conditioned Place Preference in Mice

Published on: February 18, 2016

17.9K

相关概念视频

Multiple Allele Traits01:49

Multiple Allele Traits

The Concept of Multiple Allelism
Alterations in Blood Pressure01:30

Alterations in Blood Pressure

Alterations in blood pressure, such as hypertension (high blood pressure) and hypotension (low blood pressure), significantly affect human health. Understanding these conditions' classifications, causes, and symptoms is essential for effective management and treatment.
Hypertension (High blood pressure)
Hypertension occurs when blood pressure readings consistently exceed the normal range. It is diagnosed when systolic blood pressure (the top number, indicating pressure while the heart beats)...
Neural Regulation of Blood Pressure01:18

Neural Regulation of Blood Pressure

The neural regulation of blood pressure involves intricate interactions between the autonomic nervous system (ANS) and cardiovascular system, ensuring adequate perfusion of tissues. This regulation primarily occurs through baroreceptor and chemoreceptor reflexes, involving both short-term and long-term mechanisms.
Baroreceptor Reflex
Baroreceptors, located in the carotid sinuses and aortic arch, detect changes in blood pressure. When blood pressure rises, these stretch-sensitive receptors...
Autoregulation of Blood Flow01:17

Autoregulation of Blood Flow

Autoregulation mechanisms are characterized by their inherent capacity for self-regulation without necessitating specific nervous stimulation or endocrine control. These mechanisms facilitate the adjustment of blood flow and, therefore, perfusion specific to each tissue region. This self-regulation encompasses chemical signals and myogenic controls.
Chemical Signaling in Autoregulation
Chemical signaling operates at the precapillary sphincter level, inciting either contraction or relaxation.
Principles of Pharmacogenetics: Types of Genetic Variants01:27

Principles of Pharmacogenetics: Types of Genetic Variants

The human genome is over 99.9% identical between individuals, yet genetic differences exist at millions of bases. The human genome contains approximately 3 million variant positions per individual, many of which are heterozygous, contributing to genetic diversity and individual traits. Genetic variations include single-nucleotide polymorphisms (SNPs), insertions, deletions, and copy number variations (CNVs).SNPs, the most common variation, involve single-base changes in DNA. These can be...
Pharmacogenetic Phenotypes: Alterations in Pharmacokinetics, Drug Targets and Biologic Milieu01:29

Pharmacogenetic Phenotypes: Alterations in Pharmacokinetics, Drug Targets and Biologic Milieu

Genetic variations significantly influence drug response through pharmacokinetics, receptor interactions, and biologic milieu modifications. Pharmacokinetic alterations impact drug metabolism and clearance, affecting efficacy and toxicity. Variants in drug-metabolizing enzymes, such as CYP2C9 and CYP2C19, alter drug activation and elimination. For example, CYP2C9 loss-of-function variants require lower warfarin doses to prevent excessive bleeding, while CYP2C19 variants reduce clopidogrel...