揭开基于性别的分歧:探索周围动脉疾病中的性别差异
Fouzul Kansul1, Alexander B Crichton2, Enikő Pomozi3
1College of Engineering, Texas A&M University, College Station, TX, USA.
Current atherosclerosis reports
|September 15, 2025
概括
周围动脉疾病 (PAD) 对女性的影响不成比例,导致诊断不足和治疗不足. 了解PAD的基于性别的差异对于改善女性患者的心血管结果至关重要.
科学领域:
- 心血管医学 心血管医学
- 血管外科 血管外科
- 医学研究 医学研究
背景情况:
- 周围动脉疾病 (PAD) 是心血管发病率和死亡率的重要原因之一.
- 尽管PAD与男性的患病率相似,但PAD的研究和诊断不足,特别是在女性患者中.
- 在PAD呈现,诊断,治疗和结果方面存在基于性别的差异.
研究的目的:
- 为提供PAD基于性别的差异的概述.
- 突出流行病学,病理生理学,临床表现,管理和结果方面的差异.
- 强调需要对PAD性差异进行进一步研究.
主要方法:
- 综述现有关于PAD性别差异的知识.
- 对流行病学数据的分析.
- 检查病理生理因素和临床表现.
主要成果:
- 患有PAD的女性患者的诊断和治疗不足,接受的治疗比监督炼等疗法更少.
- 吸烟,CKD和糖尿病等心血管风险因素会增加女性的PAD风险.
- 身体差异,包括女性血小板反应性增加,有助于在更严重的阶段晚期诊断.
结论:
- 在PAD流行病学,病理生理学,危险因素,呈现和治疗方面存在显著的基于性别的不平等.
- 女性患者经历了诊断不足和治疗不足,尽管治疗效益与男性相似.
- 进一步的研究对于解决PAD的性别差异和优化患者护理至关重要.
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