在患有密码性中风的患者中,穿皮关闭的卵孔的解剖特征
Maikel H M Immens1, Lars S Witte2, Abdelhak El Bouziani2
1Department of Neurology, Radboudumc, Donders Institute for Brain, Cognition and Behaviour, Nijmegen, The Netherlands.
概括
卵孔 (PFO) 关闭是密码性中风的常见情况,但20%的患者缺乏典型的危险因素. 由心脏中风小组进行的个人评估对于PFO相关的中风管理至关重要.
科学领域:
- 心脏病学 心脏病学
- 神经学 神经学
- 医学诊断 医学诊断 医学诊断
背景情况:
- 卵孔 (PFO) 是一种常见的疾病,约占总人口的25%.
- 越来越多地认为PFO是密码性中风的原因,特别是在年轻人中.
- 确定PFO是中风的原因对于适当的患者管理至关重要.
研究的目的:
- 为了检查PFO的解剖特征,在接受了密码性中风的皮肤间PFO关闭的患者中.
- 评估正在关闭的患者中增加风险的PFO特征的流行程度.
- 评估跨学科心脏病中风队 (HST) 在患者选择中的作用.
主要方法:
- 在2016年至2022年期间接受PFO关闭的患者的回顾性数据收集.
- 经食道回声心电图被用来测量PFO的解剖特征.
- 由两位经验丰富的心脏病学家进行的分析.
主要成果:
- 223名患者接受了PFO关闭,平均年龄为42.8岁.
- 超过80%的患者表现出至少一种增加风险的PFO特征 (中度至重度的分流和/或心房隔膜动脉瘤>10毫米).
- 尽管进行了HST评估,但20%的关闭的PFOs缺乏这些特定的增加风险的特征.
结论:
- 由心脏中风小组进行的个体化评估对于管理PFO的年轻中风患者至关重要.
- 在接受PFO关闭的患者中,很大一部分患者可能没有所有典型的增加风险的特征.
- 需要进一步的研究来阐明PFO患者中风机制,而没有明确的风险因素.
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