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在结肠直肠病变的内镜下粘膜解剖后,水下关闭与常规关闭:第一项比较研究

Hirotaka Oura¹, Daisuke Murakami², Harutoshi Sugiyama²

¹Department of Gastroenterology, Tokyo Women's Medical University Yachiyo Medical Center, Chiba, Japan, onmc134@gmail.com.

|September 15, 2025

概括

水下剪贴关闭 (UCC) 比常规剪贴关闭 (CCC) 更快,用于结直肠内镜下粘膜解剖 (ESD) . 这种方法提供了可比的剪贴使用和没有增加并发症的风险,使其成为一个高效的替代方案.

科学领域:

胃肠病学胃肠病学
内視鏡外科手術內視鏡外科手術
结肠直肠手术结肠直肠手术

背景情况:

结直肠病变的内镜下粘膜解剖 (ESD) 可能导致术后.
这些的有效关闭对于预防并发症至关重要.
传统的剪贴关闭 (CCC) 是一种标准方法,但人们正在寻求更快的技术.

研究的目的:

为了比较水下剪贴关闭 (UCC) 与传统剪贴关闭 (CCC) 的疗效和安全性,用于ESD后的.
评估关闭时间,剪贴使用率和并发症率.

主要方法:

89名患有≤5厘米大肠直肠病变的患者进行了回顾性研究,接受了ESD治疗.
在UCC (n=52) 和CCC (n=37) 组之间进行比较.
主要结局:完全关闭率,ESD后凝血综合征 (PECS),延迟出血,穿孔. 二次结果:关闭时间,使用的剪贴.

主要成果:

在两组所有患者中都实现了完全的关闭.
没有观察到PECS,延迟出血或穿孔的显著差异.
与CCC (11分钟;p=0.044) 相比,UCC (10分钟) 的中位关闭时间明显较短.
使用的剪辑数在UCC和CCC组之间是相似的 (中位数10; p=0.290).
切除区域和关闭方法是影响关闭时间的独立因素.

结论:

水下剪贴关闭 (UCC) 可以减少ESD后结直肠病变 ≤5厘米关闭所需的时间.
UCC显示了与CCC相比较的剪贴使用,而不会增加严重的并发症.
UCC提供了一种潜在的更有效的时间管理方法,用于管理ESD后的结直肠.

关键词:

结直肠瘤是什么意思内镜下粘膜切割进行内镜下粘膜切割.粘膜缺陷的闭合粘膜缺陷的闭合在内镜后的下粘膜切割并发症.水下剪关闭方式

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