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Updated: Jun 17, 2026

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韩国高度血清卵巢癌的综合性转录基因分析

Hyondeog Kim1, Youngwook Kim1, Juyeong Park2,3

  • 1Graduate School of Cancer Science and Policy, National Cancer Center, Goyang, Gyeonggi-do, Republic of Korea.

PLoS genetics
|September 15, 2025
PubMed
概括

这项研究确定了韩国患者高度血清性卵巢癌 (HGSOC) 中的四种转录基因亚型. 免疫反应亚型表现出高免疫细胞透率,而差异化亚型则具有免疫缺陷,这表明潜在的治疗点.

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Tumor Progression02:07

Tumor Progression

Tumor progression is a phenomenon where the pre-formed tumor acquires successive mutations to become clinically more aggressive and malignant. In the 1950s, Foulds first described the stepwise progression of cancer cells through successive stages.
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...