应对风格和人格特征在老年双相情感障碍生活没有预防药物治疗的生活
M M A Nelissen1, E J Regeer2, M M Orhan3
1Department of Psychiatry, Brain Centre, University Medical Center Utrecht, Utrecht, the Netherlands.
Journal of affective disorders
|September 15, 2025
概括
没有使用预防药物的双相情感障碍 (BD) 的老年人经常采用积极的解决问题或被动的应对方式. 在这个群体中,安慰性认知不太常见,这表明在老年双相情绪障碍 (OABD) 中有不同的情绪管理策略.
科学领域:
- 精神病学是一个精神病学.
- 老年学是指老年学的学科.
- 心理学 心理学 心理学
背景情况:
- 双相情感障碍 (BD) 中的复发预防通常包括药物治疗,自我管理和心理治疗.
- 很大一部分BD患者不坚持预防药物治疗,因此他们的情绪管理策略尚不清楚.
- 这项研究调查了老年双相情绪障碍 (OABD) 的应对风格,人格特征和童年创伤,基于预防性药物使用.
研究的目的:
- 探索那些没有使用预防药物的双相情绪障碍 (OABD) 的老年人的应对机制和人格特征.
- 确定童年创伤对OABD中药物坚持的影响.
- 确定在OABD中预防性药物使用的预测因素.
主要方法:
- 对2个荷兰OABD队列中的280名患者的横截面分析.
- 逻辑回归用于分析与药物使用有关的应对方式 (乌得勒支应对列表) 和人格特征 (NEO五因素清单).
- 相关性和相互作用分析评估了童年创伤的作用; LASSO回归确定了关键预测因素.
主要成果:
- 积极解决问题 (OR 1.25) 和被动反应 (OR 1.34) 的应对方式与不使用预防药物有关.
- 安慰性认知 (OR 0.80) 与不使用预防药物有负相关性.
- 童年虐待与积极的问题解决和被动反应相互作用;最佳预测模型解释了药物使用差异的35.5%.
结论:
- 特定的应对方式,即积极解决问题和被动反应,与OABD中预防性药物使用的减少有关.
- 在这个人群中,安慰性认知似乎与之前的药物负面相关.
- 建议对更大,多样化的年龄组和纵向数据进行进一步的研究,以验证这些发现.
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