在秘鲁全国范围内实施和评估HPV查的外部质量评估计划
Pamela Rios-Monteza1, Lesly Solis-Ponce1, Susan Espetia1
1National Center for Public Health, Peruvian National Institute of Health, Lima, Peru.
概括
秘鲁推出了第一个全国范围的人类乳头瘤病毒 (HPV) 检测质量计划. 外部质量评估 (EQA) 计划取得了很大的成功,确保了实验室间可靠的宫癌查.
科学领域:
- 在瘤学瘤学.
- 公共卫生 公共卫生
- 病毒学 病毒学
背景情况:
- 高质量的人类乳头瘤病毒 (HPV) 检测对于消除宫癌的努力至关重要.
- 秘鲁的HPV疫苗接种覆盖率不完全,需要强有力的查质量保证.
- 需要一个全国性的外部质量评估 (EQA) 计划来标准化HPV测试.
研究的目的:
- 为秘鲁的HPV查实验室建立和评估第一个全国性的EQA计划.
- 评估进行HPV测试的实验室的性能和熟练程度.
- 确保对宫癌查进行一致和可靠的HPV检测.
主要方法:
- 秘鲁HPV国家参考实验室 (NRL) 与国际HPV参考中心 (IHRC) 协调了EQA计划.
- 共有19个查实验室参与,分析了13个盲目样本的技能面板.
- 参与实验室使用Cobas 4800 HPV测定用于样本分析.
主要成果:
- 在19个实验室中,有18个 (94.7%) 符合能力标准,准确检测HPV类型和低病毒载荷.
- 一个实验室报告了阴性和低度HPV 18样本的错误阳性.
- 该计划以高的参与率和报告率证明了可行性.
结论:
- 全国范围的EQA计划在秘鲁是可行的和有效的,以确保高质量的HPV检测.
- 年度评估将保持质量保证和公平获得可靠的宫癌查.
- 未来的计划包括独立协调,扩大参与,以及秘鲁国家实验室 (NRL) 在当地制作小组.
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