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巴西结核病服务的估计成本,2023年
Elias Jabbour1, Marcia Pinto2, Ricardo E Steffen3
1Department of Medicine, McGill University, Montreal, Québec, Canada.
估计巴西结核病 (TB) 服务成本对于有效预算和实施查策略至关重要. 对抗药性结核病的较新,较短的治疗方案比较老,较长的更具成本效益.
科学领域:
- 公共卫生 公共卫生
- 卫生经济学 卫生经济学
- 传染病流行病学 传染病流行病学
背景情况:
- 扩大结核病 (TB) 查和预防对于消除巴西的结核病至关重要.
- 需要准确的结核病服务成本数据来为预算和成本效益分析提供信息.
- 这项研究提供了巴西结核病服务的基本成本估计.
研究的目的:
- 估计巴西各种结核病 (TB) 诊断和治疗服务的成本.
- 支持预算,成本效益分析和结核病控制战略的实施.
- 为了比较不同结核病治疗方案对药物敏感性和耐药性结核病的成本.
主要方法:
- 利用来自巴西五个主要城市 (马纳乌斯,里塞菲,波多阿莱格里,圣保罗,里约热内卢) 的数据库进行成本估算.
- 针对特定的TB服务组件计算的平均成本和95%的不确定性范围 (95% UR).
- 根据成人和儿科结核病诊断和治疗的国家算法,包括家庭接触调查的综合组件成本.
主要成果:
- 使用结核素皮肤测试 (TST) 或干扰素-释放试验 (IGRA) 测试儿童的结核病感染,以及3个月的异尼和利法丁 (3HP) 的成本分别为48美元 (25美元-82美元) 和67美元 (43美元-101美元).
- 对耐药结核病 (DS-TB) 的六个月治疗费用为儿童557美元 (163美元至1195美元),成人为583美元 (175美元至1252美元).
- 对抗利法抗性结核病 (RR-TB) 的较短6个月疗程比儿童和成人18个月疗程更便宜,分别为4807美元 (1559美元-10066美元) 和3518美元 (1169美元-7330美元).
结论:
- 根据诊断和治疗选择,结核病服务的成本存在显著差异.
- 这些成本数据是有效的结核病计划预算和成本效益评估的重要投入.
- 这些发现支持巴西对结核病控制措施的战略实施.
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