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Updated: Jan 6, 2026

Rapid Generation of Amyloid from Native Proteins In vitro
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碳amylation 在α-Synuclein KTKEGV重复基因中促进序列特异性氨基基基因生成

Joshna Gadhavi1,2, Sumedha Shah1, Mohini Patel1

  • 1Department of Biological Sciences and Engineering, Indian Institute of Technology Gandhinagar, Gandhinagar 382355, India.

ACS chemical neuroscience
|September 15, 2025
PubMed
概括

碳amylation,一个影响alpha-synuclein (α-syn) 结构的过程,促进其聚合. 特定的重复动机和全长的α-syn在碳化时表现出增强的粉样蛋白形成,为同核蛋白病变提供了洞察力.

关键词:
来自KTKEGV的图案来源于KTKEGV.碳amylation 的意思是碳amylation 的意思播种效率提高了播种效率.α-syn 聚合的聚合方式

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