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Updated: Jan 17, 2026

Author Spotlight: A Model to Study the Systemic and Local Dynamics of CD8+ T Cells During LN Metastasis
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淋巴结在慢性感染和检查点封锁期间为KLF2依赖的效应因子CD8+T细胞分化提供燃料

Carlson Tsui1, Leonie Heyden2,3, Lifen Wen2

  • 1Department of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Victoria, Australia. carlson.tsui@unimelb.edu.au.

Nature immunology
|September 15, 2025
PubMed
概括

耗尽的T细胞 (TPEX) 的前体维持了耗尽的CD8+ T细胞 (TEX) 的反应. 淋巴结促进TPEX和TEX细胞的分化和功能,对于慢性感染和免疫治疗至关重要.

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