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Updated: Jan 17, 2026

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Ana P S Koltun1,2, José Trobia3, Moises S Santos4

  • 1State University of Ponta Grossa, Graduate Program in Science, Ponta Grossa, PR, Brazil.

Physical review. E
|September 16, 2025
PubMed
概括

这项研究引入了用于癌症治疗的碎形模型,模拟了瘤细胞,免疫细胞和化疗之间的相互作用. 这些发现强调了治疗方案和初始条件如何显著影响癌细胞抑制.

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Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...
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