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对二维和三维介质干细胞培养物的比较代谢和转录分析,以改善治疗应用

Manju Shrestha1, Yun-Seo Kil2,3, Yunju Jo4

  • 1Department of Precision Medicine, School of Medicine, Sungkyunkwan University, Suwon, South Korea.

British journal of pharmacology
|September 16, 2025
PubMed
概括

三维 (3D) 球形培养增强介质干细胞 (MSCs) 的干度,通过改变新陈代谢来促进静止状态. 这样可以优化MSC用于组织修复和免疫调节疗法.

关键词:
两维文化是二维文化.3D球形形状的球形体.介质细胞干细胞介质细胞干细胞代谢生物组的代谢生物组翻译学 翻译学 翻译学

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Mesenchymal stem cells (MSCs) are adult stem cells that can differentiate into most connective tissue cell types, except for hematopoietic cells, depending upon the source of MSCs. For example, bone-marrow-derived MSCs (BM-MSCs) can differentiate into osteocytes, hepatocytes, and pancreatic and neuronal cells. MSCs can be isolated from various sources such as bone marrow, placenta, adipose tissue, teeth, and Wharton’s jelly, a gelatinous substance in the umbilical cord. The ease of their...
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