阻塞性睡眠呼吸暂停和阳性心房的昼夜模式加重了负担
Creuza Macedo Goes Rocha1,2, Heitor Dutra de Medeiros2, Alexandra Régia Dantas Brigido3
1Programa de Pós-graduação da Cardiologia Instituto do Coração, São Paulo, Brazil.
概括
阻塞性睡眠呼吸暂停 (OSA) 经常在患有阳性心房动 (PAF) 的患者中未被诊断出来. 喘与更多的夜间PAF发作有关,这表明昼夜模式受到干扰.
科学领域:
- 心脏病学 心脏病学
- 睡眠医学 睡眠医学
- 肺部病理学 肺部病理学
背景情况:
- 阻塞性睡眠呼吸暂停 (OSA) 是已知的心房动的贡献者.
- 有限的数据存在于与OSA相关的阳性心房动 (PAF) 的特定昼夜模式.
研究的目的:
- 调查OSA与PAF发生的关联,特别是夜间发作.
- 为了确定患有PAF的患者中OSA的患病率和不足诊断.
主要方法:
- 包括102名至少有一次PAF发作的患者在24小时的霍尔特监测中.
- 临床评估和便携式睡眠监测被用于诊断OSA (呼吸暂停-呼吸暂停指数≥15次/小时).
主要成果:
- 57%的患者患有OSA,没有先前确诊的.
- 在OSA和夜间PAF发作之间发现了显著的关联 (OR = 1.78,P = .014).
- 与没有OSA的患者相比,OSA患者在晚上10点至凌晨4点之间经历了更多的PAF发作 (P = .037).
结论:
- 在患有PAF的患者中,OSA是常见的,并且往往未被诊断出来的.
- OSA与夜间PAF发作发生率的增加有关.
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