乳房切除术后的放射治疗:一个ASTRO-ASCO-SSO临床实践指南
Rachel B Jimenez1, Yara Abdou2, Penny Anderson3
1Department of Radiation Oncology, Massachusetts General Hospital, Boston, MA.
概括
乳腺切除术后放射治疗 (PMRT) 建议用于大多数节点阳性乳腺癌患者和选择节点阴性病例. 这些指导方针涵盖PMRT的指示,体积,剂量和最佳乳腺癌治疗的技术.
科学领域:
- 在瘤学瘤学.
- 辐射瘤学 辐射瘤学
- 乳腺癌治疗方法 乳腺癌治疗方法
背景情况:
- 乳腺切除术后的放射治疗 (PMRT) 是乳腺癌管理的关键组成部分.
- 更新的指导方针至关重要,以反映迹象,技术和基于证据的实践的进展.
研究的目的:
- 为乳腺癌中使用乳腺切除术后放射治疗 (PMRT) 提供最新的建议.
- 详细说明PMRT在前期外科设置和新辅助全身疗法后的指示.
- 为PMRT提供有关适当目标体积,剂量和治疗技术的指导.
主要方法:
- 来自美国辐射瘤学会,ASCO和外科瘤学会的多学科工作组召开了会议.
- 根据对证据的系统审查,制定了建议.
- 预先定义的共识建立方法用于评分证据质量和建议强度.
主要成果:
- 在前期乳房切除术后,大多数节点阳性乳腺癌患者和选择节点阴性病例的PMRT是适用的.
- 在局部晚期疾病或残留结节疾病的新辅助疗法后推使用PMRT.
- 提供了关于目标体积,中度低分离,3D符合RT和深呼吸喘息技术的具体指导.
结论:
- 在特定乳腺癌患者群体中,PMRT在降低复发风险方面发挥着重要作用.
- 该指南为PMRT交付提供了明确的指示和技术建议.
- 重点是基于疾病阶段,对治疗的反应和病理发现的个性化治疗.
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