6岁及以下健康儿童的呼吸道肌肉强度:一项观察性研究
Kayley Noxell1, Emily Acquaye2, Vicky MacBean2
1Therapeutic Services Ltd Physiotherapy, St John's, St. John's, Newfoundland, Canada.
Pediatric pulmonology
|September 16, 2025
概括
这项研究提供了关于七岁以下儿童最大吸气 (PImax) 和呼吸 (PEmax) 肌肉强度的关键参考数据. 这些发现对于诊断和管理儿科神经肌肉疾病至关重要.
科学领域:
- 儿科肺病学 儿科肺病学
- 呼吸系统生理学 呼吸系统生理学
- 神经肌肉疾病 神经肌肉疾病
背景情况:
- 呼吸道肌肉强度评估对于神经肌肉疾病管理至关重要.
- 确定幼儿的规范性数据对于准确的临床解释至关重要.
- 对于婴儿和幼儿的呼吸压力的现有参考数据是有限的.
研究的目的:
- 在6岁及以下的健康儿童中,确定最大吸入压力 (PImax) 和最大呼气压力 (PEmax) 的参考数据.
- 提供一个连续的参考范围,从婴儿期到学龄.
- 评估PImax和PEmax测量在这个年龄组中的可重复性.
主要方法:
- 招募了健康的,满期出生的儿童,年龄在0.08-6.85岁之间.
- 使用面罩和压力传感器测量PImax和PEmax,并通过哭泣或意志力所引起的努力.
- 计算年龄,身高,体重,BMI,并评估测量可重复性.
主要成果:
- 从技术上可以接受的PImax和PEmax数据分别来自45名和38名儿童.
- PImax显示出与年龄有显著的反向关系 (斯皮尔曼的rho -0.339,p=0.046).
- 预测PImax为120+ (-3.89xage);平均PEmax为80.3 (21.7) cmH2O,没有显著的性别差异.
结论:
- 这项研究提供了第一个连续的PImax和PEmax参考范围,从婴儿期到学龄.
- 提供的参考数据和可重复性信息对于在儿科呼吸和神经肌肉评估中临床使用有价值.
- 这些数据有助于解释幼儿的呼吸肌肉强度,有助于诊断和管理.
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