自主功能对术后睡眠障碍的影响:一项前性队列研究.
Yunda Fang1,2, Yan Zhang3, Gang Wang1,2
1Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, China.
International journal of surgery (London, England)
|September 16, 2025
概括
心率变化 (HRV) 可以识别患有术后睡眠障碍 (PSD) 风险的患者. 这项研究使用HRV开发了一个早期PSD检测模型,帮助手术恢复.
科学领域:
- 心脏病学 心脏病学
- 睡眠医学 睡眠医学
- 术后恢复 术后恢复
背景情况:
- 手术后睡眠障碍 (PSD) 是常见的手术并发症.
- 早期发现PSD对于减少手术压力和促进恢复至关重要.
- 目前用于PSD风险评估的方法有限.
研究的目的:
- 研究心率变化 (HRV) 作为PSD的数字生物标志物.
- 使用HRV开发一个用于早期PSD识别的预测模型.
- 评估PSD和没有PSD的患者的自主神经系统调节.
主要方法:
- 在51名胃肠癌手术患者中评估了120小时的连续HRV.
- 在患有和没有PSD的患者之间比较HRV参数.
- 使用HRV参数开发了一个风险因素预测模型.
主要成果:
- 患有PSD的患者表现出较低的副交感音调和破坏的自主昼夜节律.
- 预测模型实现了AUC为0.815,灵敏度为0.909,特异性为0.621.
- HRV参数有效地区分了患有和没有PSD的患者.
结论:
- HRV是诊断PSD风险的有价值的非侵入性工具.
- HRV监测可以改善外科手术期间的睡眠质量管理.
- 这种方法有可能在术后期扩大使用.
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