免疫疗法和手术的融合:利用大型语言模型进行全面的文献分析
Jiahui Xiang1, Junwei Zhang2,3, Dianzhe Tian1,2
1Eight-year Medical Doctor Program, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
International journal of surgery (London, England)
|September 16, 2025
概括
与手术相结合的免疫疗法在预防癌症复发和改善生存率方面显示出有前途. 这种文献计量分析绘制了现场地图.
科学领域:
- 在瘤学瘤学.
- 免疫学 免疫学 免疫学
- 数据科学数据科学数据科学
背景情况:
- 在可操作的环境中进行免疫治疗可以改善各种癌症的结果.
- 了解电场的轨迹对于未来的进展至关重要.
研究的目的:
- 进行免疫疗法和手术研究的文献分析.
- 确定发展轨迹和未来的方向.
主要方法:
- 对541篇出版物 (2015-2024) 的图书统计分析.
- 使用了VOSviewer,CiteSpace和R包.
- 集成的LLM驱动的文本嵌入和BERTopic用于主题综合.
主要成果:
- 出版量显示,对联合免疫疗法和手术的兴趣日益增加.
- 中国和美国在出版物方面处于领先地位; 癌症免疫疗法杂志是关键期刊.
- 确定了五个研究类别;免疫检查点抑制剂 (ICI) 的最佳使用因癌症类型而异.
- 新辅助剂ICI对特定癌症有效;mRNA疫苗和瘤病毒显示出有前途.
结论:
- 用LLM驱动的建模进行图书统计分析,阐明了该领域的发展.
- 突出了未来结合免疫疗法和手术的方向.
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