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发现,优化和评估用于治疗高脂血症的新型ANGPTL3调节器

Shurui Zhang1,2,3, Jing Zhao3, Xiong Xie3

  • 1Lingang Laboratory, Shanghai 200000, China.

Journal of medicinal chemistry
|September 16, 2025
PubMed
概括

研究人员开发了一种新型的小分子,化合物20 (compound 20),可以有效抑制类似angiopoietin的蛋白3 (ANGPTL3). 这一发现为治疗超脂血症提供了一个有前途的新疗法.

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