饮用水中的和前列腺癌:智利北部基于人口的病例控制研究
Molly E Schwalb1, Catterina Ferreccio2,3, Estela Blanco2,4
1Office of Environmental Health Hazard Assessment, California Environmental Protection Agency, Oakland, California.
概括
这项研究发现,饮用水中的与前列腺癌风险之间没有联系. 在智利北部的参与者中,高暴露水平并没有增加前列腺癌的几率.
科学领域:
- 环境健康 环境健康
- 流行病学 流行病学
- 毒理学 毒理学 毒理学
背景情况:
- 饮用水中的与肺癌,膀癌和皮肤癌有关.
- 关于暴露和前列腺癌风险的数据有限.
- 智利北部提供了一个独特的环境,以研究的致癌作用,由于高暴露水平.
研究的目的:
- 调查饮用水中的暴露与前列腺癌之间的关联.
- 为了评估患有广泛暴露的人群中前列腺癌的风险.
主要方法:
- 从2015年到2019年进行了一项病例控制研究.
- 纳入了343例前列腺癌病例和337例对照病例 (年龄≥40岁).
- 收集了终身暴露,吸烟,家族病史和查数据.
主要成果:
- 23%的参与者经历过一生暴露超过800μg/L.
- 在暴露和前列腺癌的最高和最低四分位数之间没有发现显著的关联.
- 对最高与最低四分位数的调整后赔率比率为1.14 (累计) 和1.17 (平均).
结论:
- 即使在高度中,饮用水中的暴露与前列腺癌的风险增加无关.
- 这项研究表明,不是前列腺癌的风险因素.
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