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Updated: May 10, 2026

A Toolkit to Enable Hydrocarbon Conversion in Aqueous Environments
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Published on: October 2, 2012

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使用马洛尼尔-CoA供应路径工程开发一种高合成人素的大肠杆菌菌株

Takatoshi Suematsu1,2, Manami Takama1,2, Itsuki Tomita1

  • 1Graduate School of Science, Technology and Innovation, Kobe University, 1-1 Rokkodai, Nada, Kobe 657-8501, Japan.

ACS synthetic biology
|September 16, 2025
PubMed
概括

这项研究通过增加马洛尼尔-CoA的可用性,增强了大肠杆菌中微生物生产的1,3,5-三氨基氨基 (AQ256). 策略包括引入一种酸盐同化途径,并促进内源酸-CoA生物合成,实现9.6倍的产量增加.

关键词:
1,3,5-三基氨基 (AQ256) 是一种埃舍里希亚大肠杆菌 (Escherichia coli) 是一个大肠杆菌.这是一种氨酸 (Anthraquinone).马洛尼尔 - 甲是一种代谢工程是代谢工程.第二种类型的多基化合成酶.

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