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Updated: Aug 18, 2026

Microarray-based Identification of Individual HERV Loci Expression: Application to Biomarker Discovery in Prostate Cancer
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Microarray-based Identification of Individual HERV Loci Expression: Application to Biomarker Discovery in Prostate Cancer

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使用机器学习和与运动蛋白相关的基因开发前列腺癌生化复发风险签名

Weixing Wang1, Guohai Xie2, Zhonggao Wu1

  • 1Department of Urology, Ningbo Haishu People's hospital, Ningbo, Zhejiang, China.

PloS one
|September 16, 2025
PubMed
概括

这项研究开发了一种新的预后工具,使用运动蛋白相关基因 (MPRG) 来预测前列腺癌患者的生化复发 (BCR). 这些发现为个性化治疗策略和改善临床管理提供了洞察力.

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Tumor Progression02:07

Tumor Progression

Tumor progression is a phenomenon where the pre-formed tumor acquires successive mutations to become clinically more aggressive and malignant. In the 1950s, Foulds first described the stepwise progression of cancer cells through successive stages.
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...