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Updated: Jan 17, 2026

Osmotic Drug Delivery to Ischemic Hindlimbs and Perfusion of Vasculature with Microfil for Micro-Computed Tomography Imaging
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周围动脉疾病中的PCSK9:机制和治疗前景

Yue Gao1, Jing Zhang1, Nan Jiang1

  • 1Center for Hypertension and Metabolic Diseases, Department of Hypertension and Endocrinology, Army Specialty Medical Center, Army Medical University, Chongqing, China.

Science progress
|September 16, 2025
PubMed
概括

蛋白转化酶亚素/素9型 (PCSK9) 在周围动脉疾病 (PAD) 中,除了脂质调节之外,还起着关键作用. 抑制PCSK9为PAD患者提供治疗益处,尽管优化治疗策略仍然存在挑战.

关键词:
蛋白转化酶亚提利辛/凯类型9动脉样硬化 动脉样硬化脂质新陈代谢 脂质新陈代谢低密度脂蛋白受体的受体周围动脉疾病 周围动脉疾病

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A High-Throughput Luciferase Assay to Evaluate Proteolysis of the Single-Turnover Protease PCSK908:14

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