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头发的微量元素含量与儿童的生长和发育之间的关联:跨部门监控研究协议
Gulnara Batyrova1, Gulmira Umarova2, Yeskendir Umarov3
1Department of Clinical Laboratory Diagnostics, West Kazakhstan Marat Ospanov Medical University, Aktobe, Kazakhstan.
JMIR research protocols
|September 16, 2025
概括
这项研究分析了来自哈萨克斯坦西部儿童的元素概况,将微量元素与生长和健康结果联系起来. 调查结果将为环境和营养干预的公共卫生战略提供信息.
科学领域:
- 环境健康 环境健康
- 儿科健康 儿科健康
- 分析化学 分析化学
背景情况:
- 西哈萨克斯坦面临着工业活动造成的环境污染,影响儿童健康.
- 人为因素,微量元素缺乏和气候挑战加剧了儿童的健康问题.
- 儿童的成长和发展受到区域环境条件的负面影响.
研究的目的:
- 确定居住在哈萨克斯坦西部的儿童的基本特征.
- 调查元素组成和儿童身体成长指标之间的关联.
- 确定当地儿童人口中元素含量的参考值.
主要方法:
- 分析了2279名学龄儿童 (5-18岁) 的头发样本,使用诱导合血质谱法.
- 使用世界卫生组织 (WHO) 的生长标准 (体重,身高,BMI的z-score) 评估了儿童的身体成长.
- 多重线性回归分析了元素含量,增长指标和人口因素之间的关联;通过95%覆盖区间建立的参考值.
主要成果:
- 数据收集正在进行中 (2023年9月至2025年3月),分析将于2025年9月完成.
- 结果将根据性别,地理位置 (城市/农村) 和年龄组确定基本水平的差异.
- 多重回归将揭示影响儿童身体发展指标的特定化学元素.
结论:
- 鉴定出微量/宏观元素含量与儿童生长之间的关联,将为特定区域的公共卫生干预提供指导.
- 调查结果将为营养补充剂,环境修复和减少暴露于有毒元素的政策提供信息.
- 基于网络的地图和参考值将支持该地区对环境依赖疾病的未来研究.
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