涉及CHAPS的铁素的基托醇糖糖化,用于通过温和的工艺封装生物活性分子
Junrui Ma1, Runxuan Chen1, Chang Liu1
1College of Food Science and Engineering, Tianjin University of Science and Technology, Tianjin 300457, China.
Food chemistry
|September 16, 2025
概括
这项研究表明,CHAPS可以用于为EGCG等生物活性分子创建稳定的费里纳米载体. 这些修改后的费里丁提供了增强的保护和受控释放封装化合物.
科学领域:
- 生物材料科学 生物材料科学
- 纳米技术 纳米技术
- 食品科学 食品科学 食品科学
背景情况:
- 费里的结构提供了作为生物活性分子的纳米载体的潜力.
- 化学修饰可以改变费里的特性,以提高功能.
- 稳定像EGCG这样的生物活性化合物对于食品应用至关重要.
研究的目的:
- 调查CHAPS对费里修饰的作用.
- 开发一种将EGCG封装在糖化铁素中的方法.
- 评估EGCG载荷费里的稳定性和释放特征.
主要方法:
- 费里丁是用CHAPS进行预处理的.
- 奇托奥利高糖化物通过转谷氨酸酶催化反应与费里丁结合.
- 以CHAPS为媒介的方法将表甲基酸盐 (EGCG) 封装在糖化酸中.
主要成果:
- 糖基化费里呈现出更好的热和消化稳定性.
- EGCG成功封装,封装率为15.316% (重量/重量).
- 与自由EGCG相比,封装EGCG显示出增强的稳定性和持续释放特征.
结论:
- CHAPS在修改费里结构方面发挥着重要作用.
- 开发了一种温和而高效的方法来制造带EGCG的费里纳米载体.
- 这种方法提高了食品生物活性成分的稳定性和传递性.
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