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Updated: Jan 17, 2026

Polysome Fractionation and Analysis of Mammalian Translatomes on a Genome-wide Scale
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Published on: May 17, 2014

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两种微生物组代谢物竞争tRNA修饰以影响哺乳动物细胞增殖和翻译质量控制

Wen Zhang1, Kuldeep Lahry2, Denis Cipurko3

  • 1Department of Biochemistry and Molecular Biology, University of Chicago, Chicago, IL, USA.

Nature cell biology
|September 16, 2025
PubMed
概括

微生物代谢物pre-queuosine 1 (preQ1) 抑制了人类和小鼠细胞的增殖. 自然化合物queuine可以抵消preQ1的作用.

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