对于患有痴呆症的住院患者进行体育活动干预:系统性审查和元分析
Emma Elliott1,2, Jodi Ventre3,4, Sarah Kate Smith3,4
1NIHR-ARC Greater Manchester, School of Health Sciences, The University of Manchester, The University of Manchester, Jean McFarlane Building, Oxford Road, Manchester, M13 9PL, UK. emma.elliott@manchester.ac.uk.
European geriatric medicine
|September 16, 2025
概括
患有痴呆症的住院患者可能会从体力活动干预中受益,在日常生活活动中表现出较少的下降. 然而,证据有限,表明需要更多高质量的研究来证实有效性.
科学领域:
- 老年医学 老年医学
- 神经学 神经学
- 康复科学 康复科学 康复科学
背景情况:
- 住院对患有痴呆症的人来说存在风险,包括功能下降和退化.
- 正在探索体育活动干预措施,以减轻这些不良结果.
研究的目的:
- 审查基于医院的体育活动干预措施对痴呆症患者脱条件结果的有效性.
主要方法:
- 一项系统性审查搜索了五个数据库 (MEDLINE,CENTRAL,Embase,PsycINFO,CINAHL) 截至2025年1月.
- 包括6项涉及576名患有痴呆症的成年人的研究,并将各种结果的数据汇总在一起.
- 用GRADE方法来评估证据的确定性.
主要成果:
- 超分析表明,与常规护理相比,体育活动组在3个月后日常生活的基本活动减少了 (MD 1.27,95% CI 0.36-2.18).
- 在其他结果 (强度,平衡,再录取,跌倒,停留时间,妄想) 中没有发现显著的差异,即在出院或3个月后.
- 对所有结果的证据确定性被评为低或非常低.
结论:
- 目前的证据有限,导致对体力活动干预措施的好处产生不确定性,这些干预措施超出了住院痴呆症患者的通常护理范围.
- 进一步进行高质量的研究是必不可少的,以建立有效的策略,以改善这一群体的医院结果.
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