由于营养不良和系统性类固醇滥用而导致的角膜融化:一个案例报告
1Department of Ophthalmology, Kasr AlAiny Hospital, Cairo University, Cairo, 11956, Egypt. rawan.m.hosny@students.kasralainy.edu.eg.
BMC ophthalmology
|September 16, 2025
概括
滥用口服普雷迪尼索隆来增加体重导致一名年轻女性严重的角膜化和穿孔. 这一案例凸显了无监督使用皮质类固醇的危险性以及需要医疗指导的必要性.
科学领域:
- 眼科医生 眼科 眼科
- 内分泌学 在内分泌学.
- 药理学 药理学是指药理学的学科.
背景情况:
- 皮质类固醇对于治疗各种疾病至关重要.
- 无监督使用皮质类固醇,特别是口服普雷迪尼索隆,具有重大风险.
- 以前的减肥手术和减肥可能会影响患者对药物的决定.
研究的目的:
- 报告一个罕见的角膜化和穿孔的病例,原因是医疗监督的口服普雷迪尼索隆滥用.
- 为了强调用皮质类固醇自我治疗的潜在灾难性并发症.
- 强调在使用像普得尼索隆这样的强效药物之前寻求医生的建议的重要性.
主要方法:
- 一份病例报告,详细说明患有角膜并发症的患者的临床表现和治疗方法.
- 审查患者的病史,包括减肥手术和自我处方药物.
- 描述为挽救受影响眼睛而进行的紧急手术干预.
主要成果:
- 一名27岁的女性在自行服用90毫克口服普雷迪尼索隆以增加体重后,出现左角膜融化和穿孔.
- 这位患者有空腹性手术的病史和显著的体重减轻.
- 为了保护眼球,需要进行紧急构造移植手术.
结论:
- 在没有医疗监督的情况下,滥用口服普雷迪尼索隆可以导致严重的眼部并发症,包括角膜穿孔.
- 这一案例凸显了对患者自我治疗相关风险的教育至关重要的需要.
- 医疗保健提供者应建议患者在没有医疗监督的情况下使用皮质类固醇的危险性,特别是那些有减肥手术史的人.
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