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粘性环绕性接-trabeculotomy-synechiolysis与发酵与单独发酵用于慢性初级角度闭合眼镜
Ahmed S Elwehidy1, Amr Mohammed Elsayed Abdelkader2, Sherein M Hagras1
1Department of Ophthalmology, Faculty of Medicine, Mansoura University, Mansoura, Egypt.
BMC ophthalmology
|September 16, 2025
概括
粘性环绕性接 - - 皮切割 - - 合成溶解 (VCSTS) 结合法化可显著降低慢性初级角闭眼镜 (PACG) 患者的眼内压力 (IOP) 和青光眼的药物治疗需求. 与单独的化相比,这种综合方法提供了更好的外科成功.
科学领域:
- 眼科医生 眼科 眼科
- 玻璃眼的手术 玻璃眼的手术
- 外科手术的结果
背景情况:
- 慢性主角闭眼光眼 (PACG) 在控制眼内压力 (IOP) 方面面临重大挑战.
- 发酵乳化 (PE) 是PACG的一种常见的手术干预,但其与其他手术结合的有效性正在不断评估.
研究的目的:
- 在治疗慢性PACG时,将粘性环形接 - - 微粒切除 - - 合成溶解 (VCSTS) 结合发酵与单独发酵的外科结果进行比较.
- 评估IOP的长期降低和对抗葡萄糖瘤药物 (AGMs) 的需要.
主要方法:
- 一项追溯比较研究涉及88只眼睛的69名患有未经控制的PACG的患者.
- 患者接受了VCSTS与发酵乳化 (第一组) 或单独发酵乳化 (第二组).
- 结果在24个月的随访期间进行了评估,将成功定义为IOP在6-18mmHg之间,与基线相比至少减少30%,有或没有AGMs.
主要成果:
- 两组都显示出显著的IOP降低 (p<0.001) 和减少AGM使用 (p=0.035).
- 与单独的化相比,VCSTS加化组在IOP和AGM中实现了更大的减少.
- 对于VCSTS加上发泡乳化,完全成功率为95.3%,单独发泡乳化为86.7% (p=0.153). 在第一组中,轻度血是最常见的并发症.
结论:
- 单靠化,可在PACG患者中长达两年的时间内持续降低IOP,降低AGM依赖.
- 将VCSTS添加到发泡乳化中可以增强IOP和AGM的降低,从而改善手术成功,而不会产生重大并发症.
- 结合发酵乳化,VCSTS是一种有前途的手术策略,用于治疗慢性PACG.
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