与阿托皮性皮肤炎并发的食物过敏:与发病年龄和严重程度的相关性
Ismail Ozanli1, Nezihe Nefise Uluc1, Nagihan Iskender1
1From the Division of Allergy and Immunology, Department of Pediatrics, Faculty of Medicine, Kocaeli University, Kocaeli, Turkey and.
Allergy and asthma proceedings
|September 17, 2025
概括
食物敏感性 (FS) 在患有亚托皮性皮炎 (AD) 的儿童中比食物过敏 (FA) 更常见. 通过消除饮食和口服食物挑战来确认FA,以避免在AD患者中不必要的食物限制.
科学领域:
- 皮肤病学 皮肤病学
- 过敏学 过敏学
- 儿科 儿科 儿科
背景情况:
- 在阿托皮性皮炎 (AD) 患者中,食物敏感性 (FS) 和食物过敏 (FA) 的频率因研究而异.
- 需要在不同AD表型中关于FS和FA患病率的明确数据.
研究的目的:
- 根据发病年龄和严重程度来确定AD中的FS和FA频率.
- 调查小儿阿兹海默症患者中FA的风险.
主要方法:
- 在2022-2024年期间,对257名被诊断患有AD的儿童进行了回顾性分析.
- 与AD发病年龄和严重程度相关的同时存在的FA和FS的评估.
- 轻度和中度至重度的AD群体之间的FA风险的比较.
主要成果:
- 在中度至重度的AD中,FS患病率为60.3%,FA患病率为32.5%,发病时间为0-3个月.
- 在中度至重度的AD中,FS为59.6%,FA为17.4%,发病时间为4至11个月.
- 中度至重度的AD增加了FA风险的14-16倍与轻度的AD相比;没有观察到发病时间>12个月的FA.
结论:
- 在儿科阿尔茨海默氏症中,FS的发病率明显高于FA.
- 诊断AD-FA共存需要消除饮食和口服食物挑战,而不仅仅是积极的FS测试.
- 这种诊断方法可以防止阿兹海默症患者不必要的食物排泄.
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