在良性发性位置性患者中复发的风险因素和预测性名录图的构建
1Ya'an Hospital of Traditional Chinese Medicine, Ya'an, China.
Medicine
|September 17, 2025
概括
良性发性位置性 (BPPV) 的复发与失眠,抑郁,高血压,糖尿病和高脂血症有关. 一个新的预测模型有助于识别患有BPPV复发高风险的患者.
科学领域:
- 神经学 神经学
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 医疗信息学 医疗信息学
背景情况:
- 良性性发性位置性 (BPPV) 是一种常见的前体障碍.
- 在患者管理方面,BPPV的复发构成了重大挑战.
- 确定BPPV复发的预测因素对于主动干预至关重要.
研究的目的:
- 调查与BPPV复发相关的因素.
- 建立和验证BPPV复发的预测模型.
- 帮助临床医生识别高风险个体,以便及时干预.
主要方法:
- 对276名BPPV患者的回顾性研究 (2022年1月 - 2024年12月).
- 单变量和多因素后勤回归分析以确定风险因素.
- 用于可视化预测模型的nomogram构造.
- 使用Bootstrap进行内部验证和10倍交叉验证.
- 通过ROC曲线,AUC,Hosmer-Lemeshow测试,校准图和决策曲线进行性能评估.
主要成果:
- 6个月内整体复发率为25.36% (共276名患者中的70人).
- 确定了5个独立的复发风险因素:失眠 (OR=3.593),抑郁状态 (OR=3.800),高血压 (OR=4.315),糖尿病 (OR=3.216),以及高脂血症 (OR=3.912).
- 预测模型表现出良好的区分能力,适合性和稳定的性能.
结论:
- BPPV复发与失眠,抑郁状态,高血压,糖尿病和高脂血症显著相关.
- 开发的预测模型提供了良好的准确性和临床实用性.
- 这个工具可以帮助临床医生在高风险BPPV患者的积极管理和干预.
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