针对线粒体DNA复制的三 - 合诺抗生素的抗癌作用

Yuming Qiao1,2, Yuki Kida1, Xiaoyi Lai1,2

  • 1Division of Innovative Cancer Therapeutics, Chiba Cancer Center Research Institute, Chiba, Japan.

Cancer science
|September 17, 2025
PubMed
概括

称为MitoQNs的新奇奇诺隆衍生物,准线粒体DNA复制以增强癌细胞死亡. 这些化合物显示抗菌活性降低,可能降低抗生素耐药性,并在临床前模型中表现出显著的抗癌疗效.

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