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Updated: Jan 17, 2026

Conformational Evaluation of HIV-1 Trimeric Envelope Glycoproteins Using a Cell-based ELISA Assay
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Conformational Evaluation of HIV-1 Trimeric Envelope Glycoproteins Using a Cell-based ELISA Assay

Published on: September 14, 2014

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甘氨酸对HIV-1包裹和广泛中和抗体之间的相互作用的克莱德特定影响

Mrinal Arandhara1, Yogendra Kumar1, Narendra M Dixit2,3

  • 1Department of Physics, Indian Institute of Science, Bangalore 560012, India.

Journal of chemical information and modeling
|September 17, 2025
PubMed
概括

艾滋病毒-1包膜蛋白上的N链 glycans 屏蔽广泛中和抗体 (bNAbs). 这项研究模拟了HIV-1类基因组之间的甘氨酸-bNAb相互作用,揭示了屏蔽和抗体可访问性的显著差异,这对于疫苗设计至关重要.

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