在健康受试者骨矿物质密度,骨矿物质含量和瘦肉质的侧对侧差异
María Lorena Brance1,2,3, Silvana Di Gregorio4, Luis A Ramírez Stieben1,3
1Bone Biology Laboratory, School of Medicine, Rosario National University, Rosario, Santa Fe, Argentina.
Journal of bone metabolism
|September 17, 2025
概括
肢体优势影响身体组成,主导的上肢表现出更高的骨矿物质密度,含量和瘦肉量. 这些差异因性别和年龄而异,影响我们如何理解身体组成的变化.
科学领域:
- 人类解剖学和生理学 人类解剖学和生理学
- 生物医学成像学 生物医学成像学
- 运动科学 运动科学
背景情况:
- 肢体优势影响肌肉力量和日常活动,导致骨矿物质密度 (BMD),骨矿物质含量 (BMC) 和由于不对称的机械负荷而导致的瘦肉质的横向差异.
- 了解这些变异对于解释区域骨质去矿化至关重要,特别是当使用对侧肢作为参考时.
- 以前的研究表明,骨和肌肉质量存在横向差异,但需要对性别和年龄组进行全面分析.
研究的目的:
- 用双能X射线吸收计 (DXA) 分析健康成年人体内BMD,BMC和肌肉质量的侧对侧差异.
- 调查四肢优势,性别和衰老如何影响身体组成参数.
- 为健康个体提供参考数据,有助于评估涉及区域性骨质损失的情况.
主要方法:
- 横截面研究涉及802个全身DXA扫描的西班牙成年人,年龄在20-80岁.
- 排除运动员和患有骨代谢障碍的个人,以确保健康的队列.
- 自我报告的手和脚占主导地位,使用Lunar Prodigy DXA扫描仪测量了BMD,BMC和肌肉质量.
主要成果:
- 在所有测量参数中,在主导和非主导四肢之间观察到强烈的相关性 (r>0.90).
- 主导的上肢表现出明显更高的BMD (~4%),BMC (~5-6%),质 (~3-4%) 在两性.
- 在下肢的性别特异性差异被注意到,老龄化对男性和女性的BMD,BMC和瘦肉量有不同的影响.
结论:
- 肢体优势显著影响上肢体构成,与下肢相比,观察到的效果更大.
- 性别和衰老是调节四肢主导地位对BMD,BMC和瘦肉质的影响的关键因素.
- 这些发现为健康的成年人群体内身体组成的横向性和与年龄相关的变化提供了宝贵的见解.
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