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在内环增强病变的扩散加权成像

Adrien M Dupanloup¹, Craig S Brown², Karen M Vernau¹

¹Department of Surgical and Radiological Sciences, School of Veterinary Medicine, University of California, Davis, Davis, California, USA.

Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association

|September 17, 2025

概括

表面扩散系数 (ADC) 值可以帮助区分传染性脑病变. 较低的ADC值表明细菌,有助于在MRI上诊断环增强性病变,但这并非在所有感染中都可见.

科学领域:

兽医辐射学兽医辐射学
神经成像是一种神经成像.
传染病成像学传染病成像学

背景情况:

在MRI上的环增强病变,由于感染,瘤和炎症等各种病因,存在诊断挑战.
标准的MRI测序往往难以有效地区分这些病变.
扩散权重成像 (DWI) 为病变的特征提供了额外的信息.

研究的目的:

为了比较表面扩散系数 (ADC) 值的内环增强病变的传染病因与其他原因.
评估ADC值在区分传染病与非传染病环增强病变方面的有用性.
为了确定DWI的限制扩散是否是特定类型的传染性脑病变的可靠标记.

主要方法:

追溯对DWI的MRI研究和对具有环增强病变和确定的诊断的动物进行后加多T1加权成像的回顾.
创建ADC地图并选择受损和逆侧脑组织感兴趣的区域 (ROI).
计算标准化的ADC值 (rADC=ADClesion/ADCbrain) 用于定量分析.

主要成果:

与质瘤 (1.7) 和非传染性炎症病变 (1.7) 相比,内细菌的中位数rADC (0.54) 显着较低.
出血性病变的rADC值 (0.54) 与细菌相似,可能存在潜在的诊断重叠.
外细菌 (rADC 2.8) 和真菌 (rADC 1.2) 并没有始终表现出受限扩散.
在排除出血性病变时,0.65的rADC切线显示出对内细菌的高特异性 (98%) 和敏感性 (78%).

结论:

在DWI上明显的受限扩散是识别环增强病变中的内细菌的有价值指标.
然而,外包膜细菌和真菌可能不会显示受限制的扩散,限制了这一发现的普遍适用性.
ADC值,特别是rADC,有助于区分传染病与瘤或炎症环增强性病变,特别考虑出血和非细菌传染病因.

关键词:

一个的.看似的扩散系数 (ADC)扩散权重成像 (DWI) 的使用.磁共振成像 (MRI) 的使用.环环环环环环环环环环环环环

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