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在老年人中,与 вести相关的头持续时间和认知缺陷
Xiaobao Ma1,2,3, Jiali Shen1,2,3, Wei Wang1,2,3
1Department of Otorhinolaryngology-Head and Neck Surgery, Xinhua Hospital Shanghai Jiaotong University School of Medicine Shanghai China.
Alzheimer's & dementia (New York, N. Y.)
|September 17, 2025
概括
老年人的长期前体问题与认知能力下降有关,特别是在视觉空间和执行功能方面. 对于早期检测这些前体相关的认知障碍,P300延迟测试比MoCA更为敏感.
科学领域:
- 老年学是一门学科.
- 神经科学是一个神经科学.
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
背景情况:
- 在老年人群中,以头和为特征的静脉功能障碍很普遍.
- 认知障碍是老年人的一个重大问题,影响生活质量.
- 前体症状的持续时间与认知功能之间的关系需要进一步研究.
研究的目的:
- 检查 vestibular 相关的头/vertigo 持续时间与老年患者的认知功能之间的关联.
- 确定评估和管理前体相关认知障碍的临床策略.
- 为了比较P300事件相关潜力的灵敏度和蒙特利尔认知评估 (MoCA) 在检测认知缺陷方面.
主要方法:
- 100名患有前庭功能障碍的老年患者被分为短期 (n=64) 和长期 (n=36) 组.
- 为了进行比较,包括了21名健康老年人的对照组.
- 认知功能使用P300事件相关潜力 (延迟/幅度) 和蒙特利尔认知评估 (MoCA) 以域特定分析来评估.
主要成果:
- 在对照组,短期组和长期组中发现了P300延迟的显著差异 (p < 0.001).
- 在各组之间,MoCA总分数有显著的差异 (p = 0.001),视觉空间和抽象能力有显著差异.
- 症状持续时间和P300延迟时间与各种认知领域有显著的相关性,包括MoCA总得分和视觉空间能力.
结论:
- 长时间的前体相关的头/与老年人的认知缺陷有关,特别是影响视觉空间和执行功能.
- P300延迟是一个比单独的P300幅度或MoCA查更敏感的前体相关认知障碍指标.
- 建议采用联合电生理学 (P300延迟) 和神经心理学 (MoCA) 评估方法,以便在这个人群中早期和有效地检测认知障碍.
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