鼻腔腹 在伊斯法罕的Cryptosporidium分布
Zahra Ghayour1, Maryam Rahmani Dehaghani1, Sakineh Akbari2
1Department of Parasitology and Mycology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
显微镜错过了住院患者的Cryptosporidium感染,但PCR检测到这种寄生虫引起腹的流行率为0.92%. 这凸显了医疗保健机构需要敏感的诊断方法来管理密码菌病的传播.
科学领域:
- 医学寄生虫学 医学寄生虫学
- 传染性疾病 传染性疾病
- 分子诊断学 分子诊断
背景情况:
- 克里普托斯波里迪亚 spp. 导致密码化症,一种通过污染源传播的腹疾病.
- 它构成了重大的公共卫生和环境挑战,特别影响弱势群体.
- 研究通常集中在免疫力低下的个体,儿童,牲畜和水源上.
研究的目的:
- 为了调查Cryptosporidium在患有腹的住院患者中的患病率.
- 为了比较显微镜和PCR在诊断临床环境中的密码杆菌病的疗效.
- 评估Cryptosporidium在医院传播的可能性.
主要方法:
- 研究了217名患有急性或慢性腹的住院患者.
- 使用修改的Ziehl Neelsen (MZN) 染料进行显微镜检查.
- 采用嵌套聚合酶连锁反应 (PCR),针对分子检测的18SrRNA基因.
主要成果:
- 显微镜检测到0.00% (0/217) 的Cryptosporidium的流行.
- 通过PCR检测发现0.92% (2/217) 的便样本为Cryptosporidium阳性.
- 通过PCR检测发现了低,但目前的患病率被传统显微镜所遗漏.
结论:
- 由Cryptosporidium引起的鼻性腹并不常见,但在医疗机构中可能发生.
- 医院可以作为传染性疾病的潜在传播场所,如密码菌症.
- 有效的卫生管理需要了解引起医院腹的病原体的影响,特别是在发展中国家.
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