DLGAP5通过肝细胞热驱动的巨细胞代谢重编程和M1极化促进急性肝损伤

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Xianzhi Liu1, Zhiyuan Chen1, Jun Lin2

  • 1Department of Gastroenterology, Xiang'an Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, Fujian, 361000, China.

International journal of biological sciences
|September 17, 2025
PubMed
概括

热,一种被编程的细胞死亡,是急性肝损伤 (ALI) 的关键. 由METTL3介导的m6A修饰通过DLGAP5促进热,加剧ALI,但抑制提供治疗潜力.

关键词:
急性肝损伤 (ALI) 是一种严重的肝损伤.在 DLGAP5 里面,你会看到 DLGAP5.肝细胞 (HC) 是一个肝细胞.细胞间通信是细胞间的通信.巨细胞是一个巨细胞.热灭菌的发生.

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