相关实验视频

Updated: Jan 17, 2026

Analysis of Lymph Node Volume by Ultra-High-Frequency Ultrasound Imaging in the Braf/Pten Genetically Engineered Mouse Model of Melanoma

Analysis of Lymph Node Volume by Ultra-High-Frequency Ultrasound Imaging in the Braf/Pten Genetically Engineered Mouse Model of Melanoma

Published on: September 8, 2021

一种罕见的黑色素瘤变体:小细胞恶性黑色素瘤转移到淋巴结中的转移

Egemen Akincioglu¹, Tolga Baglan²

¹Department of Pathology, University of Health Science, Gulhane Training and Research Hospital, Ankara, Turkey.

Journal of cytology

|September 17, 2025

概括

这项研究呈现了一种罕见的小细胞恶性黑色素瘤 (SCMM) 转移在中枢淋巴结中的罕见病例. 对SCMM的认识至关重要,以防止其他小圆蓝细胞瘤的误诊.

科学领域:

在瘤学瘤学.
病理学病理学病理学
皮肤病学皮肤病学

背景情况:

小细胞恶性黑色素瘤 (SCMM) 是一种不常见的黑色素瘤变体.
与其他黑色素瘤类型相比,SCMM与预后较差有关.

研究的目的:

报告SCMM转移到中枢淋巴结的病例.
突出SCMM的细胞形态特征和诊断考虑因素.

主要方法:

一个54岁的男性病例研究,右手病变和中间淋巴结转移.
淋巴结的细针吸收活检.
瘤细胞的细胞学和免疫组织化学分析.

主要成果:

细胞学揭示了 discohesive 细胞,核聚合物,小细胞层和伪片.
瘤细胞对S-100,SOX10,MelanA和HMB45.5呈阳性.
友性白血病病毒整合1 (FLI1) 在超过10%的瘤细胞中呈阳性.

结论:

转移性恶性黑色素瘤可以表现出各种细胞形态特征.
SCMM是一个诊断挑战,可能会被误认为是其他小圆蓝细胞瘤.
提高SCMM的认识和准确诊断对于适当的患者管理至关重要.

关键词:

细胞学细胞学精细的针吸入精细的针.黑色素瘤是一种黑色素瘤.小细胞恶性黑色素瘤

更多相关视频

A 3D Organotypic Melanoma Spheroid Skin Model

A 3D Organotypic Melanoma Spheroid Skin Model

Published on: May 18, 2018

Injection of Syngeneic Murine Melanoma Cells to Determine Their Metastatic Potential in the Lungs

Injection of Syngeneic Murine Melanoma Cells to Determine Their Metastatic Potential in the Lungs

Published on: May 24, 2016

相关概念视频

Metastasis

Metastasis

Metastasis is the spread of cancer cells from the original site to distant locations in the body. Cancer cells can spread via blood vessels (hematogenous) as well as lymph vessels in the body.
Epithelial-to-Mesenchymal Transition
The epithelial-to-mesenchymal transition or EMT is a developmental process commonly observed in wound healing, embryogenesis, and cancer metastasis. EMT is induced by transforming growth factor-beta (TGF-β) or receptor tyrosine kinase (RTK) ligands, which further...

Skin Cancer

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...