对触摸印记和压碎细胞学与上胃肠内镜活检中的组织病理学进行比较研究
Akanksha Kalita1, Prajwala Gupta1, Kanika Rastogi1
1Department of Pathology, Atal Bihari Vajpayee Institute of Medical Sciences and Dr. Ram Manohar Lohia Hospital, Delhi, New Delhi, India.
印记和压碎细胞学对于诊断上部胃肠道疾病是有效的. 这些快速方法显示出高灵敏度和特异性,补充了对病原体的研究,以准确诊断.
科学领域:
- 胃肠病学 胃肠病学
- 细胞病理学 细胞病理学
- 在瘤学瘤学.
背景情况:
- 触摸印记和粉碎细胞学已经建立了快速,经济高效的诊断方法.
- 这些技术对于评估哨兵淋巴结,卵巢瘤和中枢神经系统瘤的病变特别有用.
- 它们在诊断上部胃肠道 (UGI) 疾病中的实用性需要进一步评估.
研究的目的:
- 为了评估UGI通道疾病的印记和压碎细胞学的诊断准确性.
- 为了比较细胞学发现与组织病理学结果.
- 评估这些方法在识别瘤和非瘤疾病中的作用.
主要方法:
- 该研究包括在1.5年内接受UGI内镜活检的患者.
- 使用Giemsa和Papanicolaou染料准备和染色触摸印记和压碎涂抹.
- 细胞学结果被系统地与相应的细胞病理学发现进行了比较.
主要成果:
- 与基因病理学相比,印记和粉碎细胞学显示出高的整体敏感性 (95.7%) 和特异性 (98.8%).
- 对于Helicobacter pylori感染,细胞学获得了71.4%的灵敏度,99%的特异性和97.19%的准确性.
- 粉碎和印记涂抹技术都表现出类似的诊断效率.
结论:
- 印记/粉碎细胞学作为UGI内镜活检的组织病理学的一个有价值的辅助.
- 这些方法可靠地帮助评估活检的充分性,并区分良性和恶性病变.
- 印象细胞学是有效的诊断特定的感染,如H. pylori,Candida和简单疹病毒.
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