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Updated: Jan 17, 2026

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鉴定KRAS突变 (G12C,G12D和G12V) 抑制剂的发现

Vikas Yadav1, Mohammad Kashif1,2, Zenab Kamalia3

  • 1School of Computational and Integrative Sciences, Jawaharlal Nehru University, New Delhi, India.

Future medicinal chemistry
|September 17, 2025
PubMed
概括

研究人员确定了针对KRAS G12V和G12C突变的新型小分子抑制剂. 这些化合物显示出有前途的抗癌活性,特别是针对KRAS驱动的瘤,支持进一步的治疗开发.

关键词:
克拉斯 (Kras) 是一个国家.在MAPK路径中.在NSCLCLC中,我们可以看到NSCLCLC.我们的PDAC是PDAC.结肠癌是什么意思结肠癌是什么意思分子动力学模拟,分子动力学模拟原则组件分析和自由能源景观.基于结构的药物设计.

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