成年人不同抗咳药片的pH调节和唾液清除率:一项随机临床试验
Saloni D Wankhede1, Prashanth K Vishwakarma2, Arun S Dodamani3
1Department of Public Health Dentistry, JMF's ACPM Dental College, Dhule, Maharashtra, India, Phone: +91 9307139321, e-mail: saloniwankhede9096@gmail.com, Orcid: https://orcid.org/0009-0007-4144-9276.
The journal of contemporary dental practice
|September 17, 2025
概括
不同的咳片显著改变唾液pH值和口腔清除,影响牙健康. 科夫莱特显示pH值下降最少,清除速度最快,这表明与TusQ和Vicks等其他类型相比,牙的风险较低.
科学领域:
- 牙科科学 牙科科学
- 口腔健康研究研究 口腔健康研究
- 药理学 药理学是指药理学的学科.
背景情况:
- 抗咳药片被广泛用于缓解咳.
- 它们对口腔健康的影响,特别是唾液pH值和清除,尚未完全理解.
- 了解这些影响对于预防牙等口腔健康问题至关重要.
研究的目的:
- 为了比较四种不同的抗咳药片对唾液pH的影响.
- 评估和比较这些药片的口服清除率.
- 评估这些药片对口腔健康的潜在影响.
主要方法:
- 40名健康成年人被分为四组 (每组n=10) 使用Strepsils,Koflet,TusQ或Vicks.
- 唾液样本在基线和每5分钟间隔收集到30分钟后的间隔.
- 唾液pH值被数字测量,口服清除时间由pH恢复到基线的时间来确定.
主要成果:
- 所有的片都导致唾液pH值下降;TusQ的下降幅度最大,Koflet的下降幅度最小.
- 科夫莱特保持了更高的pH值,并且具有最短的口服清除时间 (12.7分钟).
- 维克斯的口服清除时间最长 (19.4分钟),表明保留时间长.
结论:
- 抗咳药片显著影响唾液pH值和口腔清除.
- 具有较低pH值和较长清除时间的片具有较高的面膜侵蚀和的风险.
- 牙科专业人员应建议患者选择更安全的乳剂,并鼓励制造商开发牙友好的选择.
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