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Cryo-electron Microscopy01:28

Cryo-electron Microscopy

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Conventional electron microscopy (EM) involves dehydration, fixation, and staining of biological samples, which distorts the native state of biological molecules and results in several artifacts. Also, the high-energy electron beam damages the sample and makes it difficult to obtain high-resolution images. These issues can be addressed using cryo-EM, which uses frozen samples and gentler electron beams. The technique was developed by Jacques Dubochet, Joachim Frank, and Richard Henderson, for...
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相关实验视频

Updated: Jan 17, 2026

Directed Assembly of Elastin-like Proteins into defined Supramolecular Structures and Cargo Encapsulation In Vitro
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自组装的Eu3+综合体使得多刺激响应数据加密.

Lijuan Liang1, Xiao Yang1, Xiangyuan Yan1

  • 1State Key Laboratory of Natural Product Chemistry, Key Laboratory of Nonferrous Metal Chemistry and Resources Utilization of Gansu Province, College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou, 730000, China.

Advanced materials (Deerfield Beach, Fla.)
|September 17, 2025
PubMed
概括
此摘要是机器生成的。

研究人员开发了基于欧的新型纳米粒子 (Eu-NPs),具有三重直角刺激响应的发光. 这些先进的材料可以实现动态数据加密和物理无法克隆的功能,用于防伪应用.

关键词:
在Eu3+复合体中.信息的加密信息的加密.具有多种刺激的响应性.物理上不可克隆的函数 (PUFs)这是一个超分子组件.

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科学领域:

  • 材料科学 材料科学 材料科学
  • 纳米技术 纳米技术
  • 化学 化学 化学

背景情况:

  • 响应多刺激的发光材料对于先进的信息加密至关重要.
  • 整合直角刺激-响应性,可逆性和纳米控制提出了重大挑战.

研究的目的:

  • 开发基于Eu3+的纳米粒子 (Eu-NPs),具有三重直角刺激响应的发光 (pH/热/光).
  • 探索它们在等级加密平台和物理无法克隆的函数 (PUF) 中的应用.

主要方法:

  • 通过定制β-二甲复合物的J聚合驱动自组装 (Eu(THA) (3) 合成了Eu-NP.
  • 研究了刺激响应的发光特性,包括pH切换,热火和光调节的FRET.
  • 制造的加密平台和PUF利用了Eu-NPs的独特特征.

主要成果:

  • 在红色Eu3+排放和绿色联体聚合诱导排放 (AIE) 之间实现了可逆的pH切换.
  • 证明了带有线性热火的双模式温度计.
  • 启用UV/Vis光调制FRET,用于单颗粒开启/关闭.
  • 开发了分层加密平台 (标签,QR码,水凝) 和具有双键身份验证和高编码能力的PUF.

结论:

  • 开发的Eu-NPs为适应性反假冒提供了一个新的范式.
  • 这一策略将动态数据加密与在单个稀土纳米平台上物理无法克隆的安全性整合在一起.