建模全身动态PET微剂量数据,以预测GLYBURIDE在人类中的全身药理动力学

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Updated: Jan 17, 2026

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Determining Glucose Metabolism Kinetics Using 18F-FDG Micro-PET/CT

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Léa Comin1,2, Solène Marie2,3, Moreno Ursino1

  • 1Inserm, UMRS 1346, Université Paris Cité, Inria, HeKA, 75015, Paris, France.

Clinical pharmacokinetics
|September 17, 2025
PubMed
概括

这项研究从[11C]glyburide的全身动态PET成像开发了一个药理动力学模型. 该模型准确地描述了糖的生物分布和药物相互作用,通过PET数据推进了PK分析.

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