患有面综合征的儿童的睡眠呼吸障碍
Ganeshraj Sivaram1, Kahir Jawad2, Karim El-Kersh3
1Division of Pulmonary Critical Care and Sleep Medicine, Department of Medicine, University of Louisville School Medicine, Louisville, KY, USA.
概括
阻塞性睡眠呼吸暂停 (OSA) 在患有面综合征 (CFS) 的儿童中非常普遍,影响近70%. 部分散骨质生成 (MDO) 显著改善了这些患者的睡眠质量,特别是那些患有皮埃尔·罗宾序列 (PRS) 患者.
科学领域:
- 儿科肺病学 儿科肺病学
- 面外科手术 面外科手术
- 睡眠医学 睡眠医学
背景情况:
- 阻塞性睡眠呼吸暂停 (OSA) 是患有面综合征 (CFS) 的儿童的一个重大问题.
- 有限的数据存在于这个特定的儿科群体中OSA的流行率和管理.
- 面异常可能会使儿童在睡眠期间容易出现呼吸道阻塞.
研究的目的:
- 确定患有CFS的儿童中OSA的患病率.
- 为了描述这个队列中的多睡眠学 (PSG) 发现.
- 描述患有CFS的儿童中OSA的管理策略和结果.
主要方法:
- 在一个单一的第三级护理中心对患有CFS和PSG的18岁以下患者的回顾性图表审查数据.
- 分析病史和外科病史,以及包括呼吸暂停-呼吸暂停指数 (AHI) 和氧和度 (SpO2) 在内的PSG参数.
- 对治疗结果的评估,重点关注皮埃尔·罗宾序列 (PRS) 患者的下分心骨质生成 (MDO).
主要成果:
- 包括46名患有CFS的儿童;69.6%患有OSA,其中39.1%是严重的.
- 在16名皮埃尔·罗宾序列 (PRS) 患者中,OSA患病率为93.8%.
- 在PRS患者中,MDO显著降低了AHI,REM AHI和EtCO2,同时增加了SpO2和总睡眠时间.
结论:
- 在患有CFS的儿童中,OSA比以前认为的更为常见.
- 部分散骨质生成 (MDO) 是这种队列中OSA的主要治疗方法,并取得了显著的改善.
- 皮埃尔·罗宾序列 (PRS) 是儿童中最常见的面综合征,与OSA相关,从MDO中受益很大.
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