罗马 便秘症状加剧了痛苦的排便预测了耐火性便秘的特定亚型
Christian Lambiase1,2, Massimo Bellini1,2, Francesco Rettura1,2,3
1Gastrointestinal Unit, Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, Pisa, Italy.
Neurogastroenterology and motility
|September 17, 2025
概括
痛苦的排便投诉,当添加到罗马III标准时,显著改善了慢性便秘患者功能性排便障碍亚型的识别. 这有助于更好地照顾患者,并可能减少对广泛生理测试的需要.
科学领域:
- 胃肠病学 胃肠病学
- 结肠直肠手术 结肠直肠手术
- 生理学 生理学 生理学
背景情况:
- 功能性排便障碍 (FDD) 是严重便秘的常见原因之一.
- 诊断FDD通常需要生理学测试,如直肠测量 (ARM) 和气球驱逐测试 (BET).
- 区分FDD亚型对于有效治疗至关重要.
研究的目的:
- 评估将疼痛排便的症状添加到罗马III问卷是否可以帮助区分耐火性慢性便秘亚型.
- 为了将患者报告的症状与客观的生理发现相关联.
主要方法:
- 198名患有慢性便秘,对初始治疗没有反应的患者被纳入.
- 患者接受了数字直肠检查 (DRE) 检查疼痛,并报告疼痛的排便频率.
- 生理测试包括DRE,ARM,BET,在某些情况下,分泌学和结肠过境时间评估.
主要成果:
- 40.9%的患者报告每周疼痛的排便,43.3%的患者有DRE-温柔性.
- 48.5%的患者被诊断为FDD,主要是异能排便 (DD) 或不充分的排便推进 (IDP).
- 没有特定的预测因素被确定为IDP.
结论:
- 疼痛排便的症状是罗马III标准的关键补充,用于识别耐火性慢性便秘的特定亚型.
- 这种基于症状的方法可以提高诊断的准确性,并可能减少对昂贵的生理测试的依赖.
- 更好地识别便秘亚型,可以带来更有针对性,更有效的患者护理.
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