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Updated: Jan 17, 2026

Targeted Next-generation Sequencing and Bioinformatics Pipeline to Evaluate Genetic Determinants of Constitutional Disease
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Targeted Next-generation Sequencing and Bioinformatics Pipeline to Evaluate Genetic Determinants of Constitutional Disease

Published on: April 4, 2018

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与儿科癌症治疗相关的罕见变异与第二恶性新生体风险相关

Claire Ducos1,2,3, Brice Fresneau1,2,3,4, Filippo Rosselli5

  • 1Radiation Epidemiology Team, Center for Research in Epidemiology and Population Health, INSERM Unit 1018, Villejuif, France.

JCO precision oncology
|September 17, 2025
PubMed
概括

在RNASEL,APOBEC3F和FANCM基因的遗传变异与儿童癌症幸存者的第二恶性瘤 (SMNs) 风险增加有关. 这些发现可能有助于识别高风险个体,以提供量身定制的后续护理.

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