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Updated: Aug 7, 2026

Metabolic Characterization of Polarized M1 and M2 Bone Marrow-derived Macrophages Using Real-time Extracellular Flux Analysis
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在巨细胞激活期间,分辨与非分辨的脂动态:一个时间分辨的代谢分析

Nathan F Chiappa1, Nidhi Lal1, Edward A Botchwey2

  • 1Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University School of Medicine, Atlanta, GA, USA; Parker H. Petit Institute for Bioengineering and Bioscience, Georgia Institute of Technology, Atlanta, GA, USA.

Journal of lipid research
|September 17, 2025
PubMed
概括

巨细胞中的脂代谢在炎症期间发生变化,产生不同的细胞状态. 针对特定的代谢途径可能有助于解决炎症和预防疾病.

关键词:
陶化物是一种陶化物.这是一种炎症炎症炎症炎症.脂质组的类型脂体是指脂体的组成部分.斯芬戈辛酸盐是一种酸盐.

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Protein Dynamics in Living Cells01:19

Protein Dynamics in Living Cells

Different fluorescence-based techniques are used to study the protein dynamics in living cells. These techniques include FRAP, FRET, and PET.
Fluorescent recovery after photobleaching (FRAP) is a fluorescent-protein-based detection technique used to quantify protein movement rates within the cell. This method exposes a small portion of the cell to an intense laser beam. The laser beam causes permanent photobleaching of the fluorophore-tagged proteins in the exposed region. As the bleached...