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Updated: Jan 17, 2026

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肺动脉高血压中的SOX17:从发育到临床表型

Thomas Lacoste-Palasset1, Benoit Aguado1, Julien Grynblat1,2

  • 1Université Paris-Saclay, INSERM, UMR_S 999, Hypertension Pulmonaire: Physiopathologie and Innovation Thérapeutique (HPPIT), AP-HP, Hôpital Bicêtre, Hôpital Marie Lannelongue (Groupe Hospitalier Paris Saint Joseph), ERN-LUNG, Le Plessis Robinson, France.

European respiratory review : an official journal of the European Respiratory Society
|September 17, 2025
PubMed
概括

罕见的SOX17基因变异与肺动脉高血压 (PAH) 有关. SOX17缺乏是PAH的核心,这表明恢复SOX17的疗法可以治疗这种严重的肺病.

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