头部和部癌症查:口腔腔和口腔癌的现状
Hugh A J Kim1, Kristina Dahlstrom2, Erich M Sturgis3
1Department of Otolaryngology-Head and Neck Surgery, University of Toronto, Canada.
Otolaryngologic clinics of North America
|September 17, 2025
概括
对于无症状的成年人,不建议进行口腔癌查. 然而,由于烟草使用率较高,南亚和东南亚人可能会从口腔查中受益. 在预防口腔癌 (OPC) 方面,HPV疫苗接种至关重要.
科学领域:
- 在瘤学瘤学.
- 公共卫生 公共卫生
- 预防医学 预防医学
背景情况:
- 目前的指导方针不建议对无症状的成年人进行常规的口腔或口腔癌 (OPC) 查.
- 某些人群,如南亚和东南亚人群,口腔癌的患病率更高,可能与吸烟有关.
- 人类乳头瘤病毒 (HPV) 是口腔癌的重要危险因素.
研究的目的:
- 评估高风险人群中针对性口腔癌查计划的潜力.
- 探索针对与HPV相关的口腔关癌症的新型查范式.
- 强调HPV疫苗在癌症预防策略中的重要性.
主要方法:
- 审查目前的查建议和特定人群的癌症患病率数据.
- 在查中考虑基于生物流体的生物标志物.
- 在潜在的查方案中包括全面的头部和部检查,阴茎检查和成像方法.
主要成果:
- 目前,没有症状的成年人不建议由初级保健医生进行例行口腔癌查.
- 南亚和东南亚人群是口腔查的潜在目标群体,因为他们烟的患病率更高.
- 包括生物标志物,体检和成像在内的多模式查方法可能对与HPV相关的OPC有效.
结论:
- 针对性口腔癌查可能对特定高风险族群有益.
- 耳鼻喉科医生应该倡导和支持HPV疫苗接种,以减少HPV相关癌症的负担.
- 未来与HPV相关的OPC查策略可能涉及先进生物标志物和临床检查的组合.
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