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Updated: Jan 17, 2026

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精神分裂症风险基因SETD1A的突变导致人类神经元中突触功能失调

Xiao Su1,2, Hanwen Zhang3, Yan Hong4

  • 1Center for NeuroMetabolism, Child Health Institute of New Jersey, Rutgers Robert Wood Johnson Medical Center, 89 French Street, New Brunswick, NJ, USA.

Molecular psychiatry
|September 17, 2025
PubMed
概括

与精神分裂症 (SCZ) 相关的罕见SETD1A基因突变导致神经元功能障碍. 这些功能丧失突变影响突触传播和可塑性,为SCZ病理生理学提供了洞察力.

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